plasma concentration time profiles Search Results


plasma concentration  (Simcyp)
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Simcyp plasma concentration
Plasma Concentration, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration-time profiles and pk parameters  (Bristol Myers)
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Bristol Myers plasma concentration-time profiles and pk parameters
Plasma Concentration Time Profiles And Pk Parameters, supplied by Bristol Myers, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma bupivacaine concentration-vs-time profiles  (Pacira Inc)
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Pacira Inc plasma bupivacaine concentration-vs-time profiles
Schematic image of an injection of liposome <t>bupivacaine</t> into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.
Plasma Bupivacaine Concentration Vs Time Profiles, supplied by Pacira Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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jobin yvon plasma profiling time flight mass spectrometry (pptofms) instrument  (HORIBA Ltd)
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HORIBA Ltd jobin yvon plasma profiling time flight mass spectrometry (pptofms) instrument
Schematic image of an injection of liposome <t>bupivacaine</t> into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.
Jobin Yvon Plasma Profiling Time Flight Mass Spectrometry (Pptofms) Instrument, supplied by HORIBA Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration time profiles  (CEM Corporation)
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CEM Corporation plasma concentration time profiles
Schematic image of an injection of liposome <t>bupivacaine</t> into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.
Plasma Concentration Time Profiles, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration profiles/pk parameters  (Dawley Inc)
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Dawley Inc plasma concentration profiles/pk parameters
Schematic image of an injection of liposome <t>bupivacaine</t> into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.
Plasma Concentration Profiles/Pk Parameters, supplied by Dawley Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration profiles of ac-plp-bpi-nh 2 -2  (Dawley Inc)
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Dawley Inc plasma concentration profiles of ac-plp-bpi-nh 2 -2
Schematic image of an injection of liposome <t>bupivacaine</t> into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.
Plasma Concentration Profiles Of Ac Plp Bpi Nh 2 2, supplied by Dawley Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration-time profile of r-antidote  (Dawley Inc)
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Dawley Inc plasma concentration-time profile of r-antidote
Schematic image of an injection of liposome <t>bupivacaine</t> into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.
Plasma Concentration Time Profile Of R Antidote, supplied by Dawley Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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svl and sva plasma concentration–time profiles  (Simcyp)
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Simcyp svl and sva plasma concentration–time profiles
Modeling strategy of simvastatin lactone <t>(SVL)</t> and <t>acid</t> <t>(SVA)</t> in the selected platforms. ADME, absorption, distribution, metabolism, and excretion; DDI, drug–drug interaction; DGI, drug–gene interaction; J max , unbound maximum concentration; PBPK, physiologically‐based pharmacokinetic; PK, pharmacokinetic; SVA, simvastatin acid; SVL, simvastatin lactone; V max , maximal rate of metabolism.
Svl And Sva Plasma Concentration–Time Profiles, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration- time profiles  (Boehringer Ingelheim)
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Boehringer Ingelheim plasma concentration- time profiles
Modeling strategy of simvastatin lactone <t>(SVL)</t> and <t>acid</t> <t>(SVA)</t> in the selected platforms. ADME, absorption, distribution, metabolism, and excretion; DDI, drug–drug interaction; DGI, drug–gene interaction; J max , unbound maximum concentration; PBPK, physiologically‐based pharmacokinetic; PK, pharmacokinetic; SVA, simvastatin acid; SVL, simvastatin lactone; V max , maximal rate of metabolism.
Plasma Concentration Time Profiles, supplied by Boehringer Ingelheim, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration–time profiles in humans simulated in  (Simcyp)
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Simcyp plasma concentration–time profiles in humans simulated in
Modeling strategy of simvastatin lactone <t>(SVL)</t> and <t>acid</t> <t>(SVA)</t> in the selected platforms. ADME, absorption, distribution, metabolism, and excretion; DDI, drug–drug interaction; DGI, drug–gene interaction; J max , unbound maximum concentration; PBPK, physiologically‐based pharmacokinetic; PK, pharmacokinetic; SVA, simvastatin acid; SVL, simvastatin lactone; V max , maximal rate of metabolism.
Plasma Concentration–Time Profiles In Humans Simulated In, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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plasma concentration – time profile of r-warfarin and s- warfarin  (Dawley Inc)
90
Dawley Inc plasma concentration – time profile of r-warfarin and s- warfarin
Modeling strategy of simvastatin lactone <t>(SVL)</t> and <t>acid</t> <t>(SVA)</t> in the selected platforms. ADME, absorption, distribution, metabolism, and excretion; DDI, drug–drug interaction; DGI, drug–gene interaction; J max , unbound maximum concentration; PBPK, physiologically‐based pharmacokinetic; PK, pharmacokinetic; SVA, simvastatin acid; SVL, simvastatin lactone; V max , maximal rate of metabolism.
Plasma Concentration – Time Profile Of R Warfarin And S Warfarin, supplied by Dawley Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Schematic image of an injection of liposome bupivacaine into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.

Journal: Local and Regional Anesthesia

Article Title: Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine

doi: 10.2147/LRA.S88685

Figure Lengend Snippet: Schematic image of an injection of liposome bupivacaine into the surgical site. Notes: White arrows point to liposomes; white haze illustrates free bupivacaine contained in liposome bupivacaine solution. Image courtesy of Avenue-V Media, New York, NY, USA.

Article Snippet: This is also illustrated by the plasma bupivacaine concentration-vs-time profiles for groups 2 and 5 ( ) (Pacira Pharmaceuticals, Inc., data on file, 2011).

Techniques: Injection, Liposomes

Mean (± SD) subject-reported pain intensity scores assessed using a numeric rating scale (0= no pain; 10= worst possible pain) in adult males who received liposome bupivacaine 266 mg/20 mL (13.3 mg/mL [1.33%]; n=12) or liposome bupivacaine 266 mg/40 mL (6.7 mg/mL [0.67%]; n=12) via bilateral transversus abdominis plane infiltration for postsurgical analgesia following robotic-assisted laparoscopic prostatectomy. Notes: Republished with permission of Sternlicht A, Shapiro M, Robelen G, Vellayappan U, Tuerk IA. Infiltration of liposome bupivacaine into the transversus abdominis plane for postsurgical analgesia in robotic laparoscopic prostatectomy: a pilot study. Local Reg Anesth. 2014;7:69–74. Copyright © 2014. Permission conveyed through Copyright Clearance Center, Inc. Abbreviations: h, hours; SD, standard deviation.

Journal: Local and Regional Anesthesia

Article Title: Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine

doi: 10.2147/LRA.S88685

Figure Lengend Snippet: Mean (± SD) subject-reported pain intensity scores assessed using a numeric rating scale (0= no pain; 10= worst possible pain) in adult males who received liposome bupivacaine 266 mg/20 mL (13.3 mg/mL [1.33%]; n=12) or liposome bupivacaine 266 mg/40 mL (6.7 mg/mL [0.67%]; n=12) via bilateral transversus abdominis plane infiltration for postsurgical analgesia following robotic-assisted laparoscopic prostatectomy. Notes: Republished with permission of Sternlicht A, Shapiro M, Robelen G, Vellayappan U, Tuerk IA. Infiltration of liposome bupivacaine into the transversus abdominis plane for postsurgical analgesia in robotic laparoscopic prostatectomy: a pilot study. Local Reg Anesth. 2014;7:69–74. Copyright © 2014. Permission conveyed through Copyright Clearance Center, Inc. Abbreviations: h, hours; SD, standard deviation.

Article Snippet: This is also illustrated by the plasma bupivacaine concentration-vs-time profiles for groups 2 and 5 ( ) (Pacira Pharmaceuticals, Inc., data on file, 2011).

Techniques: Standard Deviation

Pharmacokinetic parameters of liposome bupivacaine following subcutaneous injection in rats (Pacira Pharmaceuticals, Inc., data on file, 2011) <xref ref-type= a , b " width="100%" height="100%">

Journal: Local and Regional Anesthesia

Article Title: Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine

doi: 10.2147/LRA.S88685

Figure Lengend Snippet: Pharmacokinetic parameters of liposome bupivacaine following subcutaneous injection in rats (Pacira Pharmaceuticals, Inc., data on file, 2011) a , b

Article Snippet: This is also illustrated by the plasma bupivacaine concentration-vs-time profiles for groups 2 and 5 ( ) (Pacira Pharmaceuticals, Inc., data on file, 2011).

Techniques: Injection

Mean plasma bupivacaine HCl concentration over time following subcutaneous administration of high- versus low-density liposome bupivacaine in rats (Pacira Pharmaceuticals, Inc., data on file, 2011).

Journal: Local and Regional Anesthesia

Article Title: Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine

doi: 10.2147/LRA.S88685

Figure Lengend Snippet: Mean plasma bupivacaine HCl concentration over time following subcutaneous administration of high- versus low-density liposome bupivacaine in rats (Pacira Pharmaceuticals, Inc., data on file, 2011).

Article Snippet: This is also illustrated by the plasma bupivacaine concentration-vs-time profiles for groups 2 and 5 ( ) (Pacira Pharmaceuticals, Inc., data on file, 2011).

Techniques: Clinical Proteomics, Concentration Assay

Modeling strategy of simvastatin lactone (SVL) and acid (SVA) in the selected platforms. ADME, absorption, distribution, metabolism, and excretion; DDI, drug–drug interaction; DGI, drug–gene interaction; J max , unbound maximum concentration; PBPK, physiologically‐based pharmacokinetic; PK, pharmacokinetic; SVA, simvastatin acid; SVL, simvastatin lactone; V max , maximal rate of metabolism.

Journal: CPT: Pharmacometrics & Systems Pharmacology

Article Title: Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction

doi: 10.1002/psp4.12837

Figure Lengend Snippet: Modeling strategy of simvastatin lactone (SVL) and acid (SVA) in the selected platforms. ADME, absorption, distribution, metabolism, and excretion; DDI, drug–drug interaction; DGI, drug–gene interaction; J max , unbound maximum concentration; PBPK, physiologically‐based pharmacokinetic; PK, pharmacokinetic; SVA, simvastatin acid; SVL, simvastatin lactone; V max , maximal rate of metabolism.

Article Snippet: The f 1 value for SVL and SVA plasma concentration–time profiles across doses was 44 and 78% in Simcyp compared to 38 and 37% in PK‐Sim.

Techniques: Concentration Assay

Input parameter for SVL and SVA models

Journal: CPT: Pharmacometrics & Systems Pharmacology

Article Title: Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction

doi: 10.1002/psp4.12837

Figure Lengend Snippet: Input parameter for SVL and SVA models

Article Snippet: The f 1 value for SVL and SVA plasma concentration–time profiles across doses was 44 and 78% in Simcyp compared to 38 and 37% in PK‐Sim.

Techniques: Molecular Weight, In Vitro, Permeability, Formulation, Dissolution, Solubility, Clinical Proteomics